I think it would make a difference if the snake had been inbred over various generations, but otherwise I don't think you'd encounter TOO much of a problem.
As far as the pooping thing, have you tried putting the snake in warm water/massaging the body?
1.1 ball pythons (Huxley and Marla)
~"Interestingly enough, the only thing the bowl of petunias thought was, 'Oh no, not again.'" --Douglas Adams~
* Mollie *