View Single Post
Old 08-09-03, 12:41 PM   #7 (permalink)
Posts: n/a
Piebaldism is a rare autosomal dominant disorder of melanocyte development. Piebaldism is due to an absence of melanocytes in affected skin and hair follicles (for non-reptiles) as a result of mutations of the KIT proto-oncogene and correlates with the site of the mutation within the KIT gene. Paradox albinos result from incomplete Tyrosinase blockage in some cells that allows melanin to be produced, so basically it is 'how' the genes are affected that makes the difference between piebald and paradox.