I would start small and then work your way up, some snakes will tolerate handleing all day.(not that u should do it) but it like what Invictus said it depends of the speces, corns will alwas be active, if there not active then something is probly wrong. if they are adults i would let them handle the corns about 10-20 min every other day and then work your way up. but corns in gereral are very tolerant to being handled by yong children. it would be between that and a ball python. (but ball python just kinda sit there
) well good luck!