I'm only against hybrid when it's done with animal that are rare in captivity (like diamond X jungle or angolan X ball). It seem to me that it's done for some people cause they can't find another one of the same species to breed with so they find another species... and I think it's reason to do so.
They have already hybridyze cats and dog. For exemple, they have cross wulf and dog, cat and african serval or leopard cat)
www.Hiss n' Herps.ca
0.1 White-lipped python, 1.1 Dumeril boa, 2.2 color phase Amazone tree boa, 1.1 Borneo short-tailed python, 0.1 Red blood python, 1.0 Ambon mollucan Scrub python, 2.3.1 BCC, 1.0 Irian jaya carpet python, 0.0.1 Mangrove monitor and 1.1 Bearded dragons